The Draft Environmental Impact Report is now complete, opening up the public review period for a new six-story life sciences building at 405 Industrial Road in San Carlos, San Mateo County. The development will replace a self-storage facility with nearly a quarter million square feet of leasable area. Menlo Equities and Beacon Capital Partners are joint venture partners for the project.
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405 Industrial Road pedestrian bridge at the corner of Industrial Road and Holly Street, rendering by RMW
The six-story building will yield around 411,670 square feet with 205,270 square feet of occupiable area and 206,400 square feet for the 458-car garage. The garage will occupy two below-grade levels under the 2.4-acre plot of land. The rest of the structure will rise on 1.2 acres, with about 40% of the leasable area for office use and 60% for life science laboratories.
Employees will have access to several outdoor terraces for dining and socializing. An on-site cafe will serve food throughout the day, with the cafe connected to an outdoor terrace. Exercise facilities will be included on-site. Additional parking will be included for 82 bicycles.
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405 Industrial Road pedestrian view, rendering by RMW
RMW Architecture is listed as responsible for the design. The exterior will be wrapped with a curtainwall glass skin, providing the interior with natural lighting. A series of setbacks will conform the building with the swooping southeast property border, with a rooftop terrace set back reducing the project’s perceived scale from the sidewalk.
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405 Industrial Road pedestrian bridge site map, illustration by RMW

405 Industrial Road site map, illustration by RMW
405 Industrial Road was acquired by Menlo Equities and Beacon Capital Partners in March of 2021. The property is currently a self-storage facility. Once complete, the building will be able to host up to 685 employees at a time. The estimated timeline for construction and completion has not yet been established.
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